The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease

The LDL receptor (LDLR) family has long been studied for its role in cholesterol transport and metabolism; however, the identification of ApoE4, an LDLR ligand, as a genetic risk factor for late-onset Alzheimer's disease has focused attention on the role this receptor family plays in the CNS. S...

Full description

Bibliographic Details
Main Authors: Courtney Lane-Donovan, Joachim Herz
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309974