Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology

Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology

Introduction: Cognitive deficits in people with schizophrenia (PWS) are a major predictor of disability and functioning, yet the underlying pathophysiology remains unclear. A possible role of amyloid and tau biomarkers (hallmarks of Alzheimer's disease) is still speculative in schizophrenia. Ex...

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Bibliographic Details
Main Authors: Ellen E. Lee, Charisse Winston-Gray, James W. Barlow, Robert A. Rissman, Dilip V. Jeste
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Psychiatry
Subjects:
serious mental illness
neurodegenerative disease
neurons
astrocytes
cognition
executive functioning
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2020.532624/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2020.532624/full

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