Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...

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Bibliographic Details
Main Authors: Saeed Azadi, Seyed Kazem Sadjady, Seyed Alireza Mortazavi, Nasser Naghdi, Arash Mahboubi, Roya Solaimanian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
pichia pastoris; ascorbic acid; activated carbon; pigment removal
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=3;spage=222;epage=238;aulast=Azadi

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=3;spage=222;epage=238;aulast=Azadi

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