Estrogens Determine Adherens Junction Organization and E-Cadherin Clustering in Breast Cancer Cells via Amphiregulin

Summary: Estrogens play an important role in the development and progression of human cancers, particularly in breast cancer. Breast cancer progression depends on the malignant destabilization of adherens junctions (AJs) and disruption of tissue integrity. We found that estrogen receptor alpha (ERα)...

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Bibliographic Details
Main Authors: Philip Bischoff, Marja Kornhuber, Sebastian Dunst, Jakob Zell, Beatrix Fauler, Thorsten Mielke, Anna V. Taubenberger, Jochen Guck, Michael Oelgeschläger, Gilbert Schönfelder
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220308750