Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation.

Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation.

Accumulating evidence supports the idea that secondary metabolites obtained from medicinal plants (phytometabolites) may be important contributors in the development of new chemotherapeutic agents to reduce the occurrence or recurrence of cancer. Our study focused on Dehydroleucodine (DhL), a sesqui...

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Main Authors: Natalia Bailon-Moscoso, Gabriela González-Arévalo, Gabriela Velásquez-Rojas, Omar Malagon, Giovanni Vidari, Alejandro Zentella-Dehesa, Edward A Ratovitski, Patricia Ostrosky-Wegman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550445?pdf=render

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http://europepmc.org/articles/PMC4550445?pdf=render

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