Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis

Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis

Prostate cancer (PCa) metastasis research has been hamstrung by lack of animal models that closely resemble the disease present in most patients – that metastasize to bone, are dependent on the androgen receptor (AR), and grow in an immune competent host. Here, we adapt the Myc-CaP cell line for use...

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Bibliographic Details
Main Authors: Yu Wang, Mackenzie K. Herroon, Steven P. Zielske, Leigh Ellis, Izabela Podgorski, Russell S. Taichman, Frank C. Cackowski
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Bone Oncology
Subjects:
Prostate cancer
Metastasis
Bone
Model system
Androgen receptor
Immune competent
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137421000415

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http://www.sciencedirect.com/science/article/pii/S2212137421000415

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