Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of Staphylococcus aureus

Manganese (Mn) is generally viewed as a critical nutrient that is beneficial to pathogenic bacteria due to its function as an enzymatic cofactor and its capability of acting as an antioxidant; yet paradoxically, high concentrations of this transition metal can be toxic. In this work, we demonstrate...

Full description

Bibliographic Details
Main Authors: Caroline M. Grunenwald, Jacob E. Choby, Lillian J. Juttukonda, William N. Beavers, Andy Weiss, Victor J. Torres, Eric P. Skaar
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.02915-18