Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease

Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease

Abstract Background Von Hippel-Lindau (VHL) disease is a rare oncological disease with an incidence of 1:36,000, and is characterized by the growth of different types of tumours. Haemangioblastomas in the central nervous system (CNS) and retina, renal carcinoma and pheochromocytomas are the most com...

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Bibliographic Details
Main Authors: Virginia Albiñana, Rosa María Jiménez Escribano, Isabel Soler, Luis Rodríguez Padial, Lucia Recio-Poveda, Karina Villar Gómez de las Heras, Luisa María Botella
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
von Hippel-Lindau disease (VHL)
pVHL
Hypoxia inducible factor
Retinal haemangioblastoma
Juxtapapillary and peripheral haemangioblastoma
Propranolol
Online Access:http://link.springer.com/article/10.1186/s13023-017-0664-7

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http://link.springer.com/article/10.1186/s13023-017-0664-7

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