Trichuris suis and Oesophagostomum dentatum show different sensitivity and accumulation of fenbendazole, albendazole and levamisole in vitro.

BACKGROUND: The single-dose benzimidazoles used against Trichuris trichiura infections in humans are not satisfactory. Likewise, the benzimidazole, fenbendazole, has varied efficacy against Trichuris suis whereas Oesophagostomum dentatum is highly sensitive to the drug. The reasons for low treatment...

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Bibliographic Details
Main Authors: Tina V A Hansen, Peter Nejsum, Christian Friis, Annette Olsen, Stig Milan Thamsborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3974671?pdf=render