Potential Role of Hypothalamic and Plasma Ghrelin in the Feeding Behavior of Obese Type 2 Diabetic Rats with Intraventricular Glucagon-Like Peptide-1 Receptor Agonist Intervention

Objective: To investigate the relationship of central and peripheral ghrelin during an exendin-4 (Ex-4) intervention to feeding in obese type 2 diabetic rodents. Methods: Animal models of diet-induced obesity (DIO) and type 2 diabetes were developed using male Sprague-Dawley rats fed with a high-fat...

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Bibliographic Details
Main Authors: Ke Lu, Xiaoyan Chen, Xuelian Deng, Juan Long, Jianhua Yan
Format: Article
Language:English
Published: Karger Publishers 2020-12-01
Series:Obesity Facts
Subjects:
Online Access:https://www.karger.com/Article/FullText/509956