The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

Abstract Background Annexin A1 (ANXA1) exerts anti-nociceptive effect through ANXA1 receptor formyl peptide receptor 2 (FPR2/ALX (receptor for lipoxin A4), FPR2) at the dorsal root ganglia (DRG) level. However, the mechanisms remain elucidated. By using radiant heat, hot/cold plate, tail flick, von...

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Bibliographic Details
Main Authors: Yufen Zhang, Sehui Ma, Xiao Ke, Yao Yi, Hongyan Yu, Dian Yu, Qiang Li, You Shang, Youming Lu, Lei Pei
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cell & Bioscience
Subjects:
Annexin A1
Formyl peptide receptor
Neuronal sensitivity
Nociceptive sensation
Transient receptor potential vanilloid 1
Online Access:https://doi.org/10.1186/s13578-021-00679-1

Internet

https://doi.org/10.1186/s13578-021-00679-1

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