Study on the regioselectivity of the N-ethylation reaction of N-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

Study on the regioselectivity of the N-ethylation reaction of N-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

4-Oxoquinolines are a class of organic substances of great importance in medicinal chemistry, due to their biological and synthetic versatility. N-1-Alkylated-4-oxoquinoline derivatives have been associated with different pharmacological activities such as antibacterial and antiviral. The presence o...

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Bibliographic Details
Main Authors: Pedro N. Batalha, Luana da S. M. Forezi, Maria Clara R. Freitas, Nathalia M. de C. Tolentino, Ednilsom Orestes, José Walkimar de M. Carneiro, Fernanda da C. S. Boechat, Maria Cecília B. V. de Souza
Format: Article
Language:English
Published: Beilstein-Institut 2019-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alkylation
carboxamide
oxoquinoline
quinolone
regioselectivity
Online Access:https://doi.org/10.3762/bjoc.15.35

Internet

https://doi.org/10.3762/bjoc.15.35

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