Deletion of macrophage migration inhibitory factor worsens stroke outcome in female mice

Sex is an important factor in the response to ischemic insults in both the laboratory and the clinic. Inflammation and cell death are points where sex-specific pathways diverge in stroke, and serum estrogen level status affect the response to inflammation. The cytokine macrophage migration inhibitor...

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Bibliographic Details
Main Authors: L. Christine Turtzo, Jun Li, Rebecca Persky, Sharon Benashski, Gillian Weston, Richard Bucala, Venugopal Reddy Venna, Louise D. McCullough
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neurobiology of Disease
Subjects:
MIF
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113000405