Angiotensin II blockade causes acute renal failure in eNOS-deficient mice
Compared with wild-type mice, adult endothelial nitric oxide synthase (eNOS) knockout mice (eight months of age) have increased blood pressure (BP) (126±9 mmHg vs. 100±4 mmHg), and an increased renal vascular resistance (155±16 vs. 65±4 mmHg.min/ml). Renal vascular resistance responses to i.v. admin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi - SAGE Publishing
2001-03-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.1177/14703203010020013501 |