Enhancement of in Vitro and in Vivo Function of Agarose-Encapsulated Porcine Islets by Changes in the Islet Microenvironment

The transplantation of porcine islets of Langerhans to treat type 1 diabetes may provide a solution to the demand for insulin-producing cells. Porcine islets encapsulated in agarose–agarose macrobeads have been shown to function in nonimmunosuppressed xenogeneic models of both streptozotocin-induced...

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Bibliographic Details
Main Authors: Robert W. Holdcraft, Lawrence S. Gazda, Lisa Circle, Hollie Adkins, Steven G. Harbeck, Eric D. Meyer, Melissa A. Bautista, Prithy C. Martis, Melissa A. Laramore, Horatiu V. Vinerean, Richard D. Hall, Barry H. Smith
Format: Article
Language:English
Published: SAGE Publishing 2014-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X667033