Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs

<p>Abstract</p> <p>Background</p> <p>CJ9-gD is a novel dominant-negative recombinant herpes simplex virus type 1 (HSV-1) that is completely replication-defective, cannot establish detectable latent infection <it>in </it>vivo, and expresses high levels of the...

Full description

Bibliographic Details
Main Authors: Brans Richard, Yao Feng
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/10/163