Influence of polygenic risk scores for schizophrenia and resilience on the cognition of individuals at-risk for psychosis

Influence of polygenic risk scores for schizophrenia and resilience on the cognition of individuals at-risk for psychosis

Abstract Cognitive impairment is a core feature of schizophrenia which precedes the onset of full psychotic symptoms, even in the ultra-high-risk stage (UHR). Polygenic risk scores (PRS) can be computed for many psychiatric disorders and phenotyping traits, including scores for resilience. We explor...

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Bibliographic Details
Main Authors: Qin He, Célia Jantac Mam-Lam-Fook, Julie Chaignaud, Charlotte Danset-Alexandre, Anton Iftimovici, Johanna Gradels Hauguel, Gabrielle Houle, Calwing Liao, ICAAR study group, Patrick A. Dion, Guy A. Rouleau, Oussama Kebir, Marie-Odile Krebs, Boris Chaumette
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01624-z

Internet

https://doi.org/10.1038/s41398-021-01624-z

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