Development of an Aquaporin-4 Orthogonal Array of Particle-Based ELISA for Neuromyelitis Optica Autoantibodies Detection.

Development of an Aquaporin-4 Orthogonal Array of Particle-Based ELISA for Neuromyelitis Optica Autoantibodies Detection.

Serological markers of Nuromyelitis Optica (NMO), an autoimmune disorder of the central nervous system, are autoantibodies targeting the astrocytic water channel aquaporin-4 (AQP4). We have previously demonstrated that the main epitopes for these autoantibodies (AQP4-IgG) are generated by the supram...

Full description

Bibliographic Details
Main Authors: Francesco Pisani, Paolo Settanni, Stefania Rosito, Maria Grazia Mola, Raffaele Iorio, Carla Tortorella, Maddalena Ruggieri, Maria Trojano, Maria Svelto, Antonio Frigeri, Grazia Paola Nicchia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4658006?pdf=render

Internet

http://europepmc.org/articles/PMC4658006?pdf=render

Similar Items