Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

Artemisinin and synthetic derivatives of dihydroartemisinin are known to possess various biological activities. Post-functionalization of dihydroartemisinin with triazole heterocycles has been proven to lead to enhanced therapeutic potential. By using our newly developed triazolization strategy, a l...

Full description

Bibliographic Details
Main Authors: Sampad Jana, Shabina Iram, Joice Thomas, Muhammad Qasim Hayat, Christophe Pannecouque, Wim Dehaen
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/2/303