Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression

Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies predominantly to nuclear material. Many aspects of disease pathology are mediated by the deposition of nucleic acid containing immune complexes, which also induce the type 1interferon...

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Bibliographic Details
Main Authors: Nathaniel Stearrett, Tyson Dawson, Ali Rahnavard, Prathyusha Bachali, Matthew L. Bendall, Chen Zeng, Roberto Caricchio, Marcos Pérez-Losada, Amrie C. Grammer, Peter E. Lipsky, Keith A. Crandall
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
HERV human endogenous retroviruses
lupus (SLE)
RNA-Seq
deep learning - artificial neural network (DL-ANN)
retrovirus < virus classification
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661437/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.661437/full

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