An N-terminal Region of Mot-2 Binds to p53 In Vitro

The mouse mot-2 protein was earlier shown to bind to the tumor suppressor protein, p53. The mot-2 binding site of p53 was mapped to C-terminal amino acid residues 312–352, which includes the cytoplasmic sequestration domain. In the present study, we have found that both mot-1 and mot-2 bind to p53...

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Bibliographic Details
Main Authors: Sunil C. Kaul, Roger R. Reddel, Youji Mitsui, Renu Wadhwa
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
mot
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800221