Drug-class specific impact of antivirals on the reproductive capacity of HIV.

Predictive markers linking drug efficacy to clinical outcome are a key component in the drug discovery and development process. In HIV infection, two different measures, viral load decay and phenotypic assays, are used to assess drug efficacy in vivo and in vitro. For the newly introduced class of i...

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Bibliographic Details
Main Authors: Max von Kleist, Stephan Menz, Wilhelm Huisinga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2845651?pdf=render