Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans

Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans

As the cerebellar molecular stress response is understudied, we assessed protein expression levels of hypothalamic-pituitary-adrenal (HPA) axis regulators and neurostructural markers in the cerebellum of a male PTSD mouse model and of unstressed vs. stressed male FK506 binding protein 51 (Fkbp5) kno...

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Bibliographic Details
Main Authors: Leonie Herrmann, Tim Ebert, Helena Rosen, Bozidar Novak, Alexandra Philipsen, Chadi Touma, Monika Schreckenbach, Nils C. Gassen, Theo Rein, Ulrike Schmidt
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
FKBP5 knockout
PTSD mouse model
HPA axis
FKBP52
Cerebellum
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521001090

Internet

http://www.sciencedirect.com/science/article/pii/S2352289521001090

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