Development of elastin-like polypeptide for targeted specific gene delivery in vivo

Abstract Background The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient approaches for gene delivery but often compromised...

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Bibliographic Details
Main Authors: Aena Yi, Dahye Sim, Young-Jin Lee, Vijaya Sarangthem, Rang-Woon Park
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Nanobiotechnology
Subjects:
ELP
Online Access:https://doi.org/10.1186/s12951-020-0574-z