Succinate detection in glomus jugulare paraganglioma on MRS as a marker for SDHB mutation
Succinate dehydrogenase gene mutation (SDH) is known as a cause of familial paraganglioma, and the dysfunction of SDH leads to the accumulation of succinate in the cell. Succinate detection using 1H- Magnetic Resonance Spectroscopy is reported as a highly specific biomarker for SDH mutation, but the...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
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| Series: | Otolaryngology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468548820300515 |