Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures
Abstract Background: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondar...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SciELO
2019-05-01
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Series: | Journal of Venomous Animals and Toxins including Tropical Diseases |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100311&lng=en&tlng=en |