Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures

Abstract Background: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondar...

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Bibliographic Details
Main Authors: Eduardo Octaviano Primini, José Luiz Liberato, Andreia Cristina Karklin Fontana, Wagner Ferreira dos Santos
Format: Article
Language:English
Published: SciELO 2019-05-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100311&lng=en&tlng=en

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