Galectin-9 activates and expands human T-helper 1 cells.

Galectin-9 activates and expands human T-helper 1 cells.

Galectin-9 (Gal-9) is known for induction of apoptosis in IFN-γ and IL-17 producing T-cells and amelioration of autoimmunity in murine models. On the other hand, Gal-9 induced IFN-γ positive T-cells in a sarcoma mouse model and in food allergy, suggesting that Gal-9 can have diametric effects on T-c...

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Bibliographic Details
Main Authors: Marloes J M Gooden, Valerie R Wiersma, Douwe F Samplonius, Jurjen Gerssen, Robert J van Ginkel, Hans W Nijman, Mitsuomi Hirashima, Toshiro Niki, Paul Eggleton, Wijnand Helfrich, Edwin Bremer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669208?pdf=render

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http://europepmc.org/articles/PMC3669208?pdf=render

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