Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42

Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42

Abstract Background A reliable blood-based assay is required to properly diagnose and monitor Alzheimer’s disease (AD). Many attempts have been made to develop such a diagnostic tool by measuring amyloid-β oligomers (AβOs) in the blood, but none have been successful in terms of method reliability. W...

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Bibliographic Details
Main Authors: Seong Soo A. An, Byoung-sub Lee, Ji Sun Yu, Kuntaek Lim, Gwang Je Kim, Ryan Lee, Shinwon Kim, Sungmin Kang, Young Ho Park, Min Jeong Wang, Young Soon Yang, Young Chul Youn, SangYun Kim
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Multimer detection system
Alzheimer’s disease
Amyloid-β
Oligomers
Blood biomarker
Synthetic amyloid-β
Online Access:http://link.springer.com/article/10.1186/s13195-017-0310-6

Internet

http://link.springer.com/article/10.1186/s13195-017-0310-6

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