QsrO a novel regulator of quorum-sensing and virulence in Pseudomonas aeruginosa.

In Pseudomonas aeruginosa, the production of many secreted virulence factors is controlled by a quorum-sensing (QS) circuit, constituted of transcriptional activators (LasR, RhlR, PqsR) and their cognate signaling molecules (3-oxo-C12-HSL, C4-HSL, PQS). QS is a cooperative behavior that is beneficia...

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Bibliographic Details
Main Authors: Thilo Köhler, Hajer Ouertatani-Sakouhi, Pierre Cosson, Christian van Delden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923755?pdf=render