Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: A longitudinal cohort study.

BACKGROUND:Cerebral white matter hyperintensities (WMHs) on MRI are common and associated with vascular and functional outcomes. However, the relationship between WMHs and longitudinal trajectories of functional status is not well characterized. We hypothesized that whole brain WMHs are associated w...

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Bibliographic Details
Main Authors: Mandip S Dhamoon, Ying-Kuen Cheung, Yeseon Moon, Janet DeRosa, Ralph Sacco, Mitchell S V Elkind, Clinton B Wright
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC5860694?pdf=render