Declining antibody levels to Trypanosoma cruzi correlate with polymerase chain reaction positivity and electrocardiographic changes in a retrospective cohort of untreated Brazilian blood donors.

Declining antibody levels to Trypanosoma cruzi correlate with polymerase chain reaction positivity and electrocardiographic changes in a retrospective cohort of untreated Brazilian blood donors.

<h4>Background</h4>Although infection with Trypanosoma cruzi is thought to be lifelong, less than half of those infected develop cardiomyopathy, suggesting greater parasite control or even clearance. Antibody levels appear to correlate with T. cruzi (antigen) load. We test the associatio...

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Bibliographic Details
Main Authors: Lewis F Buss, Léa Campos de Oliveira-da Silva, Carlos H V Moreira, Erika R Manuli, Flavia C Sales, Ingra Morales, Clara Di Germanio, Cesar de Almeida-Neto, Sonia Bakkour, Paul Constable, Marcelo M Pinto-Filho, Antonio L Ribeiro, Michael Busch, Ester C Sabino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008787

Internet

https://doi.org/10.1371/journal.pntd.0008787

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