HIF1α Regulates Early Metabolic Changes due to Activation of Innate Immunity in Nuclear Reprogramming

Summary: Innate immune signaling has recently been shown to play an important role in nuclear reprogramming, by altering the epigenetic landscape and thereby facilitating transcription. However, the mechanisms that link innate immune activation and metabolic regulation in pluripotent stem cells rema...

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Bibliographic Details
Main Authors: Chun Liu, Hongyue Ruan, Farhan Himmati, Ming-Tao Zhao, Christopher C. Chen, Merna Makar, Ian Y. Chen, Karim Sallam, Edward S. Mocarski, Danish Sayed, Nazish Sayed
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671120300278