TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage
The vertebrate TATA-binding protein (TBP) paralogue (TBPL2) is only expressed in growing oocytes, where TBP is absent. Here the authors highlight a unique role for the TBPL2/TFIIA complex in the establishment of the oocyte transcriptome by using a specific TSS recognition code.
Bibliographic Details
Main Authors: |
Changwei Yu,
Nevena Cvetesic,
Vincent Hisler,
Kapil Gupta,
Tao Ye,
Emese Gazdag,
Luc Negroni,
Petra Hajkova,
Imre Berger,
Boris Lenhard,
Ferenc Müller,
Stéphane D. Vincent,
László Tora |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
|
Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-020-20239-4
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