AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

AimIt is well-established that angiotensin II exerts a dampening effect on the baroreflex within the nucleus tractus solitarii (NTS), the principal brainstem site for termination of baroreceptor afferents and which is densely populated with gamma-aminobutyric acid (GABA)ergic neurons and nerve termi...

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Bibliographic Details
Main Authors: Laura Légat, Ilse Smolders, Alain G. Dupont
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
angiotensin II
gamma-aminobutyric acid (GABA)
mean arterial pressure
nucleus tractus solitarii
nitric oxide
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00460/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00460/full

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