Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys
Protection from neutralization-resistant SIV variants is particularly difficult to achieve by vaccination. Here, Keeleet al. use sieve analysis and show that TRIM5a restrictive rhesus monkeys are protected from neutralization-resistant SIVsmE660 variants by an adenovirus prime, env protein boost vac...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15740 |