Hedgehog Signaling, a Critical Pathway Governing the Development and Progression of Hepatocellular Carcinoma

Hedgehog Signaling, a Critical Pathway Governing the Development and Progression of Hepatocellular Carcinoma

Hedgehog (Hh) signaling is a classic morphogen in controlling embryonic development and tissue repairing. Aberrant activation of Hh signaling has been well documented in liver cancer, including hepatoblastoma, hepatocellular carcinoma (HCC) and cholangiocarcinoma. The present review aims to update t...

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Bibliographic Details
Main Authors: Jia Ding, Hui-Yan Li, Li Zhang, Yuan Zhou, Jian Wu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
hedgehog signaling
GLI1/2
hepatocellular carcinoma
cancer-initiating cells
drug resistance
metastasis
Online Access:https://www.mdpi.com/2073-4409/10/1/123

Internet

https://www.mdpi.com/2073-4409/10/1/123

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