Chromatographic and Computational Screening of Lipophilicity and Pharmacokinetics of Newly Synthesized Betulin-1,4-quinone Hybrids

Lipophilicity is one of the most important parameters determining the pharmacodynamic and pharmacokinetic properties, as well as the toxicity of many compounds. The subject of the research was to determine the lipophilicity of betulin-1,4-quinone hybrids using thin layer chromatography in reverse ph...

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Bibliographic Details
Main Authors: Monika Kadela-Tomanek, Maria Jastrzębska, Elwira Chrobak, Ewa Bębenek, Stanisław Boryczka
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/9/2/376