Bushen Huoxue Attenuates Diabetes-Induced Cognitive Impairment by Improvement of Cerebral Microcirculation: Involvement of RhoA/ROCK/moesin and Src Signaling Pathways

Bushen Huoxue Attenuates Diabetes-Induced Cognitive Impairment by Improvement of Cerebral Microcirculation: Involvement of RhoA/ROCK/moesin and Src Signaling Pathways

Type 2 Diabetes mellitus (T2DM) is closely correlated with cognitive impairment and neurodegenerative disease. Bushen Huoxue (BSHX) is a compound Chinese medicine used clinically to treat diabetes-induced cognitive impairment. However, its underlying mechanisms remain unclear. In the present study,...

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Bibliographic Details
Main Authors: Yuan Li, Quan Li, Chun-Shui Pan, Li Yan, Bai-He Hu, Yu-Ying Liu, Lei Yang, Ping Huang, Shao-Yang Zhao, Chuan-She Wang, Jing-Yu Fan, Xue-Mei Wang, Jing-Yan Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
diabetes-induced cognitive impairment
bushen huoxue prescription
neuron damage
AGEs/RAGE/RhoA
Src
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00527/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00527/full

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