Ex vivo HIV entry into blood CD4+ T cells does not predict heterosexual HIV acquisition in women.

BACKGROUND:A blood-based assay that could quantify HIV susceptibility would be very valuable for HIV prevention research. Previously, we developed and validated an ex vivo, flow-based, HIV entry assay to assess genital HIV susceptibility in endocervical CD4+ T cells. METHODS:Here we assessed whether...

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Bibliographic Details
Main Authors: Vineet Joag, Aida Sivro, Nonhlanhla Yende-Zuma, Hajra Imam, Natasha Samsunder, Quarraisha Abdool Karim, Salim Abdool Karim, Lyle McKinnon, Rupert Kaul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6037376?pdf=render