Recent Progress on Liver Kinase B1 (LKB1): Expression, Regulation, Downstream Signaling and Cancer Suppressive Function

Recent Progress on Liver Kinase B1 (LKB1): Expression, Regulation, Downstream Signaling and Cancer Suppressive Function

Liver kinase B1 (LKB1), known as a serine/threonine kinase, has been identified as a critical cancer suppressor in many cancer cells. It is a master upstream kinase of 13 AMP-activated protein kinase (AMPK)-related protein kinases, and possesses versatile biological functions. LKB1 gene is mutated...

Full description

Bibliographic Details
Main Authors: Ren-You Gan, Hua-Bin Li
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
liver kinase B1
LKB1
cancer
AMPK
MARK
Online Access:http://www.mdpi.com/1422-0067/15/9/16698

Internet

http://www.mdpi.com/1422-0067/15/9/16698

Similar Items