OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum

The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO) mice to investigate its roles in telencephalon development after neurulation (approximately embryonic day 9.0). We conducted transcriptional profiling an...

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Bibliographic Details
Main Authors: Renée V. Hoch, Susan Lindtner, James D. Price, John L.R. Rubenstein
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715006555