BRAF mutations may identify a clinically distinct subset of glioblastoma

Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF v...

Full description

Bibliographic Details
Main Authors: Samantha N. McNulty, Katherine E. Schwetye, Cole Ferguson, Chad E. Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Dahiya
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99278-w