TGF-β/Smad signaling in renal fibrosis

TGF-β/Smad signaling in renal fibrosis

TGF-β (transforming growth factor-β) is well identified as a central mediator in renal fibrosis. TGF-β initiates canonical and non-canonical pathways to exert multiple biological effects. Among them, Smad signaling is recognized as a major pathway of TGF- signaling in progressive renal fibrosis. Du...

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Bibliographic Details
Main Authors: Xiao-Ming eMeng, Patrick Ming-Kuen Tang, Jun eLi, Hui Y eLan
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Physiology
Subjects:
Therapeutics
mechanisms
TGF-β
renal fibrosis
Smads Mediators
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00082/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00082/full

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