Cartilage Intermediate Layer Protein 1 Suppresses TGF-β Signaling in Cardiac Fibroblasts

Cartilage Intermediate Layer Protein 1 Suppresses TGF-β Signaling in Cardiac Fibroblasts

Background: Since transforming growth factor (TGF)-β1-induced cardiac fibrosis following myocardial infarction (MI) leads to heart failure and poor clinical prognosis, we aimed to identify a novel and unknown target for cardiac fibrosis related to the TGF-β signaling. Method and result: We performed...

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Bibliographic Details
Main Authors: Kazuhiro Shindo, Masanori Asakura, Kyung-Duk Min, Shin Ito, Hai Ying Fu, Satoru Yamazaki, Ayako Takahashi, Miki Imazu, Hiroki Fukuda, Yuri Nakajima, Hiroshi Asanuma, Tetsuo Minamino, Seiji Takashima, Naoto Minamino, Naoki Mochizuki, Masafumi Kitakaze
Format: Article
Language:English
Published: Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) 2017-06-01
Series:International Journal of Gerontology
Subjects:
cardiac fibroblast
cardiac fibrosis
cartilage intermediate layer protein 1
myocardial infarction
transforming growth factor-β
Online Access:http://www.sciencedirect.com/science/article/pii/S1873959817300066

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http://www.sciencedirect.com/science/article/pii/S1873959817300066

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