Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA
Extremely compact environments can inhibit protein interactions by preventing 3-dimensional diffusion. Here the authors show that an 11-amino acid long peptide can function as a ‘molecular sled’, able to transport cargo linearly along DNA to enable interactions.
Main Authors: | Walter F. Mangel, William J. McGrath, Kan Xiong, Vito Graziano, Paul C. Blainey |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10202 |
Similar Items
-
Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA
by: Mangel, Walter F., et al.
Published: (2016) -
Molecular sled sequences are common in mammalian proteins
by: Xiong, Kan, et al.
Published: (2016) -
Concussions in Sledding Sports and the Unrecognized “Sled Head”: A Systematic Review
by: Melissa D. McCradden, et al.
Published: (2018-09-01) -
An investigative study of eleven families after hospitalization of husband with tuberculosis
by: McGrath, Margaret Anne
Published: (2017) -
A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
by: Xiong, Kan, et al.
Published: (2018)