Brownian dynamics simulation of cytochrome c diffusion and binding with cytochrome c1 in mitochondrial crista

Cytochrome c (Cc) protein shuttles electrons from respiratory chain complex III — from cytochrome c1 (Cc1) subunit — to complex IV during oxidative phosphorylation, in intermembrane space of mitochondria and cristae lumen. With Leigh syndrome (LS), the crista lumen width (CLW) increases, and ATP pro...

Full description

Bibliographic Details
Main Authors: Abaturova Anna M., Brazhe Nadezda A., Kovalenko Ilya B., Riznichenko Galina Yu, Rubin Andrei B.
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:ITM Web of Conferences
Online Access:https://www.itm-conferences.org/articles/itmconf/pdf/2020/01/itmconf_mmb2019_04001.pdf