The role of integration and clonal expansion in HIV infection: live long and prosper

Abstract Integration of viral DNA into the host genome is a central event in the replication cycle and the pathogenesis of retroviruses, including HIV. Although most cells infected with HIV are rapidly eliminated in vivo, HIV also infects long-lived cells that persist during combination antiretrovir...

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Bibliographic Details
Main Authors: Elizabeth M. Anderson, Frank Maldarelli
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-018-0448-8