The danger signal S100B integrates pathogen- and danger-sensing pathways to restrain inflammation.

Humans inhale hundreds of Aspergillus conidia without adverse consequences. Powerful protective mechanisms may ensure prompt control of the pathogen and inflammation. Here we reveal a previously unknown mechanism by which the danger molecule S100B integrates pathogen- and danger-sensing pathways to...

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Bibliographic Details
Main Authors: Guglielmo Sorci, Gloria Giovannini, Francesca Riuzzi, Pierluigi Bonifazi, Teresa Zelante, Silvia Zagarella, Francesco Bistoni, Rosario Donato, Luigina Romani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423669/?tool=EBI