Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration

Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration

Morphogenesis of hierarchical vascular networks depends on the integration of multiple biomechanical signals by endothelial cells, the cells lining the interior of blood vessels. Expansion of vascular networks arises through sprouting angiogenesis, a process involving extensive cell rearrangements a...

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Bibliographic Details
Main Authors: Joana R Carvalho, Isabela C Fortunato, Catarina G Fonseca, Anna Pezzarossa, Pedro Barbacena, Maria A Dominguez-Cejudo, Francisca F Vasconcelos, Nuno C Santos, Filomena A Carvalho, Claudio A Franco
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
angiogenesis
collective cell migration
mechanotransduction
adherens junctions
vinculin
non-canonical Wnt signaling
Online Access:https://elifesciences.org/articles/45853

Internet

https://elifesciences.org/articles/45853

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